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A Comparative Study of Neuroendocrine Heterogeneity in Small Cell Lung Cancer and Neuroblastoma

12 May 2023

Abstract excerpt

Lineage plasticity has long been documented in both small cell lung cancer (SCLC) and neuroblastoma, two clinically distinct neuroendocrine (NE) cancers. In this study, we quantified the NE features of cancer as NE scores and performed a systematic comparison of SCLC and neuroblastoma. We found neuroblastoma and SCLC cell lines have highly similar molecular profiles and shared therapeutic sensitivity. In...

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Lung Cancer Research Studies
Neuroblastoma Research and Treatments
Neuroendocrine Tumor Research Advances

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37171983
DOI: 10.1158/1541-7786.mcr-23-0002

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