Article

Mapping the convergence of genes for coronary artery disease onto endothelial cell programs

2022-11-04

Abstract excerpt

Genome-wide association studies (GWAS) have discovered thousands of risk loci for common, complex diseases, each of which could point to genes and gene programs that influence disease. For some diseases, it has been observed that GWAS signals converge on a smaller number of biological programs, and that this convergence can help to identify causal genes 1–6 . However, identifying such convergence remains challeng...

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Literature Corpus work: d921696e-cf62-5dbc-9d2a-3144ec6736b6
DOI: 10.1101/2022.11.01.514606

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