Article

Parallel RNA and DNA analysis after Deep-sequencing (PRDD-seq) reveals cell type specific lineage patterns in human brain

2020-04-20

Abstract excerpt

Elucidating the lineage relationships among different cell types is key to understanding human brain development. Here we developed P arallel R NA and D NA analysis after D eep- seq uencing (PRDD-seq), which combines RNA analysis of neuronal cell types with analysis of nested spontaneous DNA somatic mutations as cell lineage markers, identified from joint analysis of single cell and bulk DNA sequencing by sin...

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Literature Corpus work: d902cc80-e1af-5da1-9880-b98c5517c50d
DOI: 10.1101/2020.04.19.046904

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