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Article

Genetic mosaicism in the human brain: from lineage tracing to neuropsychiatric disorders.

Nature reviews. Neuroscience - 1 May 2022

Bizzotto Sara, Walsh Christopher A

Abstract excerpt

Genetic mosaicism is the result of the accumulation of somatic mutations in the human genome starting from the first postzygotic cell generation and continuing throughout the whole life of an individual. The rapid development of next-generation and single-cell sequencing technologies is now allowing the study of genetic mosaicism in normal tissues, revealing unprecedented insights into their clonal architecture...

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PMID: 35322263
DOI: 10.1038/s41583-022-00572-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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