Article

Simultaneous Identification of Brain Cell Type and Lineage via Single Cell RNA Sequencing

2021-01-01

Abstract excerpt

<h4>ABSTRACT</h4> Acquired mutations are sufficiently frequent such that the genome of a single cell offers a record of its history of cell divisions. Among more common somatic genomic alterations are loss of heterozygosity (LOH). Large LOH events are potentially detectable in single cell RNA sequencing (scRNA-seq) datasets as tracts of monoallelic expression for constitutionally heterozygous single nucleotide va...

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Literature Corpus work: 6fbcefd4-a773-5efe-80dd-cec7a5f5629a
DOI: 10.1101/2020.12.31.425016

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