Article

Afterload-induced Decreases in Fatty Acid Oxidation Develop Independently of Increased Glucose Utilization

2024-09-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Metabolic substrate utilization in HFpEF (heart failure with preserved ejection fraction), the leading cause of heart failure worldwide, is pivotal to syndrome pathogenesis and yet remains ill defined. Under resting conditions, oxidation of free fatty acids (FFA) is the predominant energy source of the heart, supporting its unremitting contractile activity. In the context of...

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Literature Corpus work: d80866d6-a74d-506e-bae1-07394e81142c
DOI: 10.1101/2024.09.17.613531

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