Article

G-quadruplex formation on specific surface-exposed regions of the human ribosomal RNA

2018-10-05

Abstract excerpt

<h4>ABSTRACT</h4> Profound similarities and critical differences mark ribosomes across phylogeny. The ribosomal core, approximated by the prokaryotic ribosome, is universal, yet mammalian ribosomes are nearly twice as large as those of prokaryotes. Differences in size are due in part to rRNA expansion segments. Here we show rRNA tentacles of Expansion Segment 7 (ES7) of Homo sapiens can form G-quadruplexes in vi...

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Literature Corpus work: d67357a7-55c5-57b6-a86c-90e89b55fe66
DOI: 10.1101/435594

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