Article

Diversity of ribosomes at the level of rRNA variation associated with human health and disease

2023-02-02

Abstract excerpt

<h4>Summary</h4> Ribosomal DNA and RNA (rDNA and rRNA) sequences are usually discarded from sequencing analyses. But with hundreds of copies of rDNA genes it is unknown whether they possess sequence variations that form different types of ribosomes that affect human physiology and disease. Here, we developed an algorithm for variant-calling between paralog genes (termed RGA) and compared rDNA variations found in...

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Identifiers and source

Literature Corpus work: 934c3273-0643-5e4f-ba06-166b78e51eed
DOI: 10.1101/2023.01.30.526360

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