Article

LKB1 acts as a critical brake for the glucagon-mediated fasting response

2022-01-30

Abstract excerpt

As important as the fasting response is for survival, an inability to shut it down once nutrients become available can lead to exacerbated disease and severe wasting. The liver is central to transitions between feeding and fasting states, with glucagon being a key initiator of the hepatic fasting response. However, the precise mechanisms controlling fasting are not well defined. One potential mediator of these tra...

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Literature Corpus work: d5d8e79c-4791-5444-9e19-e28491549b61
DOI: 10.1101/2022.01.29.478228

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