Article

Loss of flavin adenine dinucleotide (FAD) impairs sperm function and male reproductive advantage in <i>C. elegans</i>

2018-10-30

Abstract excerpt

<h4>ABSTRACT</h4> Exposure to environmental stress is clinically established to influence male reproductive health, but the impact of normal cellular metabolism on sperm quality is less well-defined. Here we show that impaired mitochondrial proline catabolism, reduces energy-storing flavin adenine dinucleotide (FAD) levels, alters mitochondrial dynamics toward fusion, and leads to age-related loss of sperm qualit...

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Literature Corpus work: d4e199ce-e8f2-53ad-ae14-f4fd2ea827c3
DOI: 10.1101/456863

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