Article

Enhanced Branched-Chain Amino Acid Metabolism Improves Age-Related Reproduction in <i>C. elegans</i>

2023-02-10

Abstract excerpt

Reproductive aging is one of the earliest human aging phenotypes, and mitochondrial dysfunction has been linked to oocyte quality decline. However, it is not known which mitochondrial metabolic processes are critical for oocyte quality maintenance with age. To understand how mitochondrial processes contribute to C. elegans oocyte quality, we characterized the mitochondrial proteomes of young and aged wild-type an...

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Literature Corpus work: e93f185c-b666-5a58-9808-1fe1d0dd5952
DOI: 10.1101/2023.02.09.527915

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