Article

Aging and sperm signals alter DNA break formation and repair in the <i>C. elegans</i> germline

2022-06-06

Abstract excerpt

Female reproductive aging is associated with decreased oocyte quality and fertility. The nematode Caenorhabditis elegans is a powerful system for understanding the biology of aging and exhibits age-related reproductive defects that are analogous to those observed in many mammals, including dysregulation of DNA repair. C. elegans germline function is influenced simultaneously by both reproductive aging and signal...

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Literature Corpus work: 742d7db2-44d5-5134-a8ab-6d0c74c15537
DOI: 10.1101/2022.06.06.494960

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