Article

The killifish germline regulates longevity and somatic repair in a sex-specific manner

2023-12-18

Abstract excerpt

Classical evolutionary theories propose tradeoffs between reproduction, damage repair, and lifespan. However, the specific role of the germline in shaping vertebrate aging remains largely unknown. Here, we use the turquoise killifish ( N. furzeri ) to genetically arrest germline development at discrete stages, and examine how different modes of infertility impact life-history. We first construct a comprehensive s...

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Literature Corpus work: 0e4b66f3-a82c-5993-8849-0a936b1e89fc
DOI: 10.1101/2023.12.18.572041

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