Article

A conserved role of Parkinson-associated DJ-1 metabolites in sperm motility, mitosis, and embryonic development

2021-01-17

Abstract excerpt

Fertility rates in the developing world have dramatically dropped in the last decades. This drop is likely due to a decline in sperm quality and women having children at older ages. Loss of function mutations in DJ-1 , a Parkinson’s associated gene, are linked to alterations in multiple cellular processes such as mitochondrial activity, ROS production or sperm motility and lead to an early onset of Parkinson’s di...

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Literature Corpus work: ba2f8617-774c-5dac-8132-b85739b10ca5
DOI: 10.1101/2021.01.16.426934

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