Article

Genetic and Chemical Controls of Sperm Fate and Spermatocyte Dedifferentiation in <em>Caenorhabditis elegans</em>

2022-12-21

Abstract excerpt

Using the nematode C. elegans germline as a model system, we previously reported that PUF-8 (a PUF RNA-binding protein) and LIP-1 (a dual-specificity phosphatase) repress sperm fate at 20°C and the dedifferentiation of spermatocytes into mitotic cells (termed "spermatocyte dedifferentiation") at 25°C. Thus, double mutants lacking both PUF-8 and LIP-1 produce excess sperm at 20°C, and their spermatocyte...

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Literature Corpus work: d7bc836b-5d29-59b7-8cf5-549cd733d9b8
DOI: 10.20944/preprints202212.0391.v1

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