Article

Roles for the RNA polymerase III regulator MAFR-1 in regulating sperm quality in <i>Caenorhabditis elegans</i>

2020-04-28

Abstract excerpt

<h4>ABSTRACT</h4> The negative regulator of RNA polymerase (pol) III mafr-1 has been shown to affect RNA pol III transcript abundance, lipid biosynthesis and storage, progeny output, and lifespan. We deleted mafr-1 from the Caenorhabditis elegans genome and found that animals lacking mafr-1 replicated many phenotypes from previous RNAi-based studies, but strikingly not the oocyte-related reproductive phenotyp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3832dbf8-d463-5a8d-8631-64026ab84e6b
DOI: 10.1101/2020.04.27.064121

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Roles for the RNA polymerase III regulator MAFR-1 in regulating sperm quality in <i>Caenorhabditis elegans</i>DOI 10.1101/2020.04.27.064121Read

ADR-2 regulates fertility and oocyte fate in <i>C. elegans</i>Semantic proximity Read

The PAF1 complex cell-autonomously promotes oogenesis in <i>Caenorhabditis elegans</i>Semantic proximity Read

The <i>pos-1</i> 3ʹ untranslated region governs germline specification and proliferation to ensure reproductive robustnessSemantic proximity Read

A Transcription Factor Functional Atlas of Germline DevelopmentSemantic proximity Read

A stress-dependent postembryonic role for the core CPA factor CFIM-1 in germline integritySemantic proximity Read

Construction of a germline-specific RNAi tool in <i>C. elegans</i>Semantic proximity Read

Identification of essential genes in <i>Caenorhabditis elegans</i> through whole genome sequencing of legacy mutant collectionsSemantic proximity Read

An RNAi-based suppressor screen identifies interactors of the Myt1 ortholog of Caenorhabditis elegans.Semantic proximity Read

Aging and sperm signals alter DNA break formation and repair in the <i>C. elegans</i> germlineSemantic proximity Read

Loss of flavin adenine dinucleotide (FAD) impairs sperm function and male reproductive advantage in <i>C. elegans</i>Semantic proximity Read

Mediator-29 Limits <i>Caenorhabditis elegans</i> FecunditySemantic proximity Read

CCAR-1 has a novel role in regulating the <i>Caenorhabditis elegans</i> germlineSemantic proximity Read