Article

Quinomycin A reduces cyst progression in Polycystic Kidney Disease

2020-10-19

Abstract excerpt

Polycystic kidney disease (PKD) is a genetic disorder that affects cilia homeostasis and causes progressive growth of tubular-derived cysts within the kidney. Efforts to find safer drugs for PKD have increased in the past few years after the successful launch of tolvaptan, the first approved drug to combat autosomal dominant PKD progression. Here we investigate the effects of Quinomycin A on progression of PKD. Qu...

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Literature Corpus work: d44600c7-4320-5976-95f3-45f267f93f1d
DOI: 10.1101/2020.10.18.344689

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