Article

<i>Ankhd1</i> enhances polycystic kidney disease development via promoting proliferation and fibrosis

2020-03-06

Abstract excerpt

<h4>ABSTRACT</h4> Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic kidney disorder resulting in 10% of patients with renal failure. The molecular events responsible for the relentless growth of cysts are not defined. Thus, identification of novel drivers of ADPKD may lead to new therapies. Ankyrin Repeat and Single KH domain-1 (ANKHD1) controls cancer cell proliferation, yet its rol...

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Literature Corpus work: 7fee1665-a91b-523b-bbbd-83a5048a7907
DOI: 10.1101/2020.03.04.977017

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