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Renal ciliopathies: promising drug targets and prospects for clinical trials

4 May 2023

Abstract excerpt

INTRODUCTION: Renal ciliopathies represent a collection of genetic disorders characterized by deficiencies in the biogenesis, maintenance, or functioning of the ciliary complex. These disorders, which encompass autosomal dominant polycystic kidney disease (ADPKD), autosomal recessive polycystic kidney disease (ARPKD), and nephronophthisis (NPHP), typically result in cystic kidney disease, renal fibrosis, and a...

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PMID: 37243567
DOI: 10.1080/14728222.2023.2218616

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