Article
Polycystic kidney diseases: from molecular discoveries to targeted therapeutic strategies.
Cellular and molecular life sciences : CMLS - 1 Feb 2008
Ibraghimov-Beskrovnaya O, Bukanov N
Abstract excerpt
Polycystic kidney diseases (PKDs) represent a large group of progressive renal disorders characterized by the development of renal cysts leading to end-stage renal disease. Enormous strides have been made in understanding the pathogenesis of PKDs and the development of new therapies. Studies of autosomal dominant and recessive polycystic kidney diseases converge on molecular mechanisms of cystogenesis, including...
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