Article

SnapHiC: a computational pipeline to map chromatin contacts from single cell Hi-C data

2020-12-15

Abstract excerpt

Single cell Hi-C (scHi-C) analysis has been increasingly used to map the chromatin architecture in diverse tissue contexts, but computational tools to define chromatin contacts at high resolution from scHi-C data are still lacking. Here, we describe SnapHiC, a method that can identify chromatin loops at high resolution and accuracy from scHi-C data. We benchmark SnapHiC against HiCCUPS, a common tool for mapping c...

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Literature Corpus work: 4c565d31-5ab6-500a-ac4d-cd66e8a11367
DOI: 10.1101/2020.12.13.422543

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