Article

Improving chromatin-interaction prediction using single-cell open-chromatin profile and making insight about the cis-regulatory landscape of the human brain

2020-12-30

Abstract excerpt

Single-cell open-chromatin profiles have the potential to reveal the pattern of chromatin-interaction in a cell-type. However, currently available cis-regulatory network prediction methods using single-cell open-chromatin profiles focus more on local chromatin-interactions despite the fact that long-range interaction among genomic sites plays a significant role in gene regulation. Here, we propose a method that pr...

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Literature Corpus work: 950900e9-6ff9-5bb2-93ac-02870e4730e8
DOI: 10.1101/2020.12.29.424732

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