Article

Mapping enhancer-gene regulatory interactions from single-cell data

2024-11-24

Abstract excerpt

Mapping enhancers and their target genes in specific cell types is crucial for understanding gene regulation and human disease genetics. However, accurately predicting enhancer-gene regulatory interactions from single-cell datasets has been challenging. Here, we introduce a new family of classification models, scE2G, to predict enhancer-gene regulation. These models use features from single-cell ATAC-seq or multio...

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Literature Corpus work: b94ebf61-3bb1-510e-8d8d-db9a11b9de67
DOI: 10.1101/2024.11.23.624931

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