Article

SnapHiC-D: a computational pipeline to identify differential chromatin contacts from single cell Hi-C data

2022-08-06

Abstract excerpt

Single cell Hi-C (scHi-C) has been used to map genome organization in complex tissues. However, computational tools to detect dynamic chromatin contacts from scHi-C datasets in development and through disease pathogenesis are still lacking. Here, we present SnapHiC-D, a computational pipeline to identify differential chromatin contacts (DCCs) between two scHi-C datasets. Compared to methods designed for bulk Hi-C...

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Literature Corpus work: e27e53ff-1636-5f2c-b87c-ab7e9a3c85e4
DOI: 10.1101/2022.08.05.502991

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