Article

Pooled optical screens in human cells

2018-08-02

Abstract excerpt

Large-scale genetic screens play a key role in the systematic discovery of genes underlying cellular phenotypes. Pooling of genetic perturbations greatly increases screening throughput, but has so far been limited to screens of enrichments defined by cell fitness and flow cytometry, or to comparatively low-throughput single cell gene expression profiles. Although microscopy is a rich source of spatial and temporal...

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Literature Corpus work: d05af7b6-061a-5b82-a3a7-63772e813b35
DOI: 10.1101/383943

Open publication

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