Linking live-cell behavior to transcriptional responses across perturbations using dynamic caging

Abstract excerpt

<h4>ABSTRACT</h4> Single-cell technologies, encompassing molecular, morphological, and functional assays, have emerged as cornerstones of modern biological research and discovery. However, current experimental methods often fail to explicitly link these ‘omic’ modalities, especially in live cells or longitudinally through time, impeding the study of multi-scale interactions and mechanisms of regulation. CellCage...

Topics

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• Cell Separation
• Clustered Regularly Interspaced Short Palindromic Repeats
• CRISPR-Cas Systems
• Flow Cytometry
• Genetic Testing
• Mammals
• Phenotype
• Single-cell and spatial transcriptomics

Identifiers and source

Literature Corpus work

1e62683f-8350-55f6-b493-0c63ab10c6b6

DOI

10.64898/2026.05.05.723043