Article

Neural mechanisms of disease pathology and cognition in young-onset Alzheimer’s Disease variants

2024-03-15

Abstract excerpt

Late-onset Alzheimer’s disease is consistently associated with alterations in the default-mode network (DMN)—a large-scale brain network associated with self-related processing and memory. However, the functional organization of DMN is far less clear in young-onset Alzheimer’s disease (YOAD). We assessed resting-state DMN effective connectivity in two common YOAD variants (i.e., amnestic variant (n = 26) and poste...

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Literature Corpus work: cebbe14f-d189-5af0-ad96-125113bf7f25
DOI: 10.1101/2024.03.11.24304042

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