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Article

The Effects of Gene Mutations on Default Mode Network in Familial Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2017

Li Xiaozhen, Westman Eric, Thordardottir Steinunn, Ståhlbom Anne Kinhult, Almkvist Ove, Blennow Kaj, Wahlund Lars-Olof, Graff Caroline

Abstract excerpt

Familial Alzheimer's disease (FAD) mutations have very high penetrance but age at onset and rate of disease progression differ. Neuroimaging and cerebrospinal fluid (CSF) examinations in mutation carriers (MCs) may provide an opportunity to identify early biomarkers that can be used to track disease progression from presymptomatic to the dementia stages of disease. The default mode network (DMN) is a resting...

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Identifiers

PMID: 27911308
DOI: 10.3233/JAD-160730

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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