Article
Spectral dynamic causal modelling of resting-state fMRI: an exploratory study relating effective brain connectivity in the default mode network to genetics.
Statistical applications in genetics and molecular biology - 31 Aug 2020
Nie Yunlong, Opoku Eugene, Yasmin Laila, Song Yin, Wang Jie, Wu Sidi, Scarapicchia Vanessa, Gawryluk Jodie, Wang Liangliang, Cao Jiguo, Nathoo Farouk S
Abstract excerpt
We conduct an imaging genetics study to explore how effective brain connectivity in the default mode network (DMN) may be related to genetics within the context of Alzheimer's disease and mild cognitive impairment. We develop an analysis of longitudinal resting-state functional magnetic resonance imaging (rs-fMRI) and genetic data obtained from a sample of 111 subjects with a total of 319 rs-fMRI scans from the...
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