Article

Amyloid-β and tau pathologies relate to distinctive brain dysconnectomics in preclinical autosomal dominant Alzheimer’s disease

2021-07-04

Abstract excerpt

<h4>ABSTRACT</h4> The human brain is composed of functional networks that have a modular topology, where brain regions are organized into communities that form internally dense (segregated) and externally sparse (integrated) subnetworks that underlie higher-order cognitive functioning. It is hypothesized that amyloid-β and tau pathology in preclinical Alzheimer’s disease (AD) spread through functional networks, d...

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Literature Corpus work: 04f127ee-e2fd-55be-867a-0554f61f4fbd
DOI: 10.1101/2021.07.03.450933

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