Back to search

Article

The relationship between shared and differentiating genetic liability for schizophrenia and bipolar disorder and cognition and educational attainment in the UK Biobank

2025-02-16

Abstract excerpt

<h4>Importance</h4> Further understanding how genetic liabilities to schizophrenia (SZ) and bipolar disorder (BD) are related to cognition and educational attainment (EA) indicates important differences between these conditions that are relevant to future research and interventions. <h4>Objective</h4> To determine how fractions of genetic liability that are shared between, and differentiate, SZ and BD, are associa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ce1722a5-348f-56e3-acae-0f2d1fcb51a2
DOI
10.1101/2025.02.13.25322048
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The relationship between shared and differentiating genetic liability for schizophrenia and bipolar disorder and cognition and educational attainment in the UK BiobankDOI 10.1101/2025.02.13.25322048
Splitting schizophrenia: divergent cognitive and educational outcomes revealed by genomic structural equation modelling.Semantic proximity
Modifiable risk factors and risk of schizophrenia and bipolar disorder across severities of genetic risk.Semantic proximity
Association of polygenic liabilities for schizophrenia and bipolar disorder with educational attainment and cognitive aging.Semantic proximity
Proof of concept: Molecular prediction of schizophrenia riskSemantic proximity
Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia.Semantic proximity
Pathway-based polygenic risk scores for schizophrenia and associations with clinical and neuroimaging phenotypes in UK BiobankSemantic proximity
Joint effects of childhood adversity and genetic risk for psychosis on psychopathology in the UK Biobank.Semantic proximity
Cognitive pleiotropy reveals disorder-specific and shared biology for schizophrenia and bipolar disorderSemantic proximity
The impact of educational attainment, intelligence and intellectual disability on schizophrenia: a Swedish population-based register and genetic study.Semantic proximity
Use of multiple Polygenic Risk Scores for distinguishing Schizophrenia-spectrum disorder and Affective psychosis categories; the EUGEI studySemantic proximity
Polygenic Risk Scores Differentiating Schizophrenia From Bipolar Disorder Are Associated With Premorbid Intelligence in Schizophrenia Patients and Healthy Subjects.Semantic proximity
Polygenic Scores for Schizophrenia and Educational Attainment Predict Global Functioning Across Psychiatric Hospitalization Among People with SchizophreniaSemantic proximity
Select a neighboring publication to make it the new centre.