Article
Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia.
Nature communications - 6 Aug 2018
Bansal V, Mitjans M, Burik C A P, Linnér R K, Okbay A, Rietveld C A, Begemann M, Bonn S, Ripke S, de Vlaming R, Nivard M G, Ehrenreich H, Koellinger P D
Abstract excerpt
Higher educational attainment (EA) is negatively associated with schizophrenia (SZ). However, recent studies found a positive genetic correlation between EA and SZ. We investigate possible causes of this counterintuitive finding using genome-wide association study results for EA and SZ (N = 443,581) and a replication cohort (1169 controls; 1067 cases) with deeply phenotyped SZ patients. We find strong genetic...
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