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Article

Joint effects of childhood adversity and genetic risk for psychosis on psychopathology in the UK Biobank.

Psychological medicine - 7 Apr 2026

Lu Zheng-An, Ploner Alexander, Bergen Sarah E

Abstract excerpt

BACKGROUND: The individual effects of genetic factors and adverse childhood experiences (ACEs) on risk of psychosis, including schizophrenia (SCZ) and bipolar disorder (BIP), have been widely acknowledged, but their interaction effects on individual psychopathological symptoms remain unclear. METHODS: Based on data from 163,704 individuals in the UK Biobank, we investigated the joint effects of polygenic risk...

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Identifiers

PMID: 41943949
DOI: 10.1017/S0033291726104012
PMCID: PMC13079213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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