Article

Forward genetic screen of human transposase genomic rearrangements

2016-07-01

Abstract excerpt

<h4>Background: </h4> Numerous human genes encode potentially active DNA transposases or recombinases, but our understanding of their functions remains limited due to shortage of methods to profile their activities on endogenous genomic substrates. <h4>Results: </h4>. To enable functional analysis of human transposase-derived genes, we combined forward chemical genetic hypoxanthine-guanine phosphoribosyltransfera...

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Literature Corpus work: cc749d0b-21d9-5d6b-a577-0c5cdfb003ba
DOI: 10.1101/061770

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