Article

A high throughput screen for active human transposable elements

2017-09-22

Abstract excerpt

<h4>ABSTRACT</h4> Transposable elements (TEs) are mobile genetic sequences that randomly propagate within their host’s genome. This mobility has the potential to affect gene transcription and cause disease. However, TEs are technically challenging to identify, which complicates efforts to assess the impact of TE insertions on disease. Here we present a targeted sequencing protocol and computational pipeline to id...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 07fdcafb-5ec0-5983-8f1f-e6c385e41fdb
DOI: 10.1101/192708

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A high throughput screen for active human transposable elementsDOI 10.1101/192708Read

A high throughput screen for active human transposable elements.Semantic proximity Read

Active Human Transposable Elements: Long-Read Sequencing Technologies, Computational Analysis, and Implications for Human DiseaseSemantic proximity Read

Mobile element scanning (ME-Scan) by targeted high-throughput sequencing.Semantic proximity Read

Transposable element-mediated rearrangements are prevalent in human genomesSemantic proximity Read

Comprehensive identification of transposable element insertions using multiple sequencing technologies.Semantic proximity Read

T-lex2: genotyping, frequency estimation and re-annotation of transposable elements using single or pooled next-generation sequencing dataSemantic proximity Read

HiTea: a computational pipeline to identify non-reference transposable element insertions in Hi-C dataSemantic proximity Read

Natural genetic variation caused by transposable elements in humans.Semantic proximity Read

Mobile element biology: new possibilities with high-throughput sequencing.Semantic proximity Read

3DSNP 2.0: update and expansion of the noncoding genomic variant annotation database.Semantic proximity Read

Systematic comparative benchmarking of computational methods for the detection of transposable elements in long-read sequencing dataSemantic proximity Read

Multi-ancestry GWAS reveals loci linked to human variation in LINE-1- and Alu-insertion numbersSemantic proximity Read