Article

Genome-wide Polygenic Risk Scores Predict Risk of Glioma and Molecular Subtypes

2024-01-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Polygenic risk scores (PRS) aggregate the contribution of many risk variants to provide a personalized genetic susceptibility profile. Since sample sizes of glioma genome-wide association studies (GWAS) remain modest, there is a need to find efficient ways of capturing genetic risk factors using available germline data. <h4>Methods</h4> We developed a novel PRS (PRS-CS) tha...

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Literature Corpus work: cbfef54c-1e6e-53de-9a4c-1568ab7dbd82
DOI: 10.1101/2024.01.10.24301112

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