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Article

A Weighted Genetic Risk Score of Adult Glioma Susceptibility Loci Associated with Pediatric Brain Tumor Risk.

Scientific reports - 2 Dec 2019

Adel Fahmideh Maral, Lavebratt Catharina, Tettamanti Giorgio, Schüz Joachim, Röösli Martin, Kjaerheim Kristina, Grotzer Michael A, Johansen Christoffer, Kuehni Claudia E, Lannering Birgitta, Schmidt Lisbeth S, Darabi Hatef, Feychting Maria

Abstract excerpt

Genetic risk score (GRS) is used to demonstrate the genetic variants contributing to the polygenic architecture of complex diseases. By using a GRS, we have investigated the additive impact of the known adult glioma susceptibility loci on the pediatric brain tumor (PBT) risk and assessed the proportion of PBT heritability attributable to these susceptibility loci. A GRS was generated for PBTs based on the alleles...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31792337
DOI: 10.1038/s41598-019-54701-1
PMCID: PMC6889151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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