Genome-Wide Association Studies in Glioma.

doi:10.1158/1055-9965.EPI-17-1080

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Article

Genome-Wide Association Studies in Glioma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2018

Kinnersley Ben, Houlston Richard S, Bondy Melissa L

Abstract excerpt

Since the first reports in 2009, genome-wide association studies (GWAS) have been successful in identifying germline variants associated with glioma susceptibility. In this review, we describe a chronological history of glioma GWAS, culminating in the most recent study comprising 12,496 cases and 18,190 controls. We additionally summarize associations at the 27 glioma-risk SNPs that have been reported so far....

Topics

Alleles
Brain Neoplasms
Genetic Predisposition to Disease
Genome-Wide Association Study
Glioma
History, 21st Century
Humans
International Cooperation
Polymorphism, Single Nucleotide

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PMID: 29382702
DOI: 10.1158/1055-9965.EPI-17-1080
PMCID: PMC5931394

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