Article

Tandem repeat variation shapes immune cell type-specific gene expression

2024-11-04

Abstract excerpt

Tandem repeats (TRs) - highly polymorphic, repetitive sequences across the human genome - are important regulators of gene expression but remain underexplored due to challenges in accurate genotyping and analysis 1 . Here, we generate new whole genome and single-cell RNA sequencing from >5.4 million blood-derived cells across 1,925 individuals in two cohorts [Cuomo et al. , accompanying manuscript], and perform...

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Literature Corpus work: cb79b74e-0bdd-5b28-a3e7-dbdde412a740
DOI: 10.1101/2024.11.02.621562

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