Article
Deciphering the genetic control of immune cell function at single-cell resolution: Disease-Specific Cis-eQTLs analysis of COVID-19.
Immunogenetics - 31 Mar 2026
Romanova E I, Tychinin D I, Shaymardanov A M, Akimov V E, Korobeinikova A V, Shiryagin V V, Guskova N I, Astafieva V A, Shingaliev A S, Antonova O A, Golubnikova L A, Mitrofanov S I, Grammatikati K S, Yudin V S, Yudin S M, Makhotenko A V, Keskinov A A, Kraevoy S A, Snigir E A, Volchkov P Yu, Svetlichnyy D V, Skvortsova V I
Abstract excerpt
Integrating whole-genome sequencing with single-cell RNA-seq data enhances the current understanding of how genomic differences across humans contribute to variations in gene activity. eQTL discovery offers a potent method for decoding genomic regulation and identifying population-specific genomic variants associated with gene expression differences. The current development of single-cell sequencing technologies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.