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Enhancement of CRISPR-Cas12a System through Universal Circular RNA Design

2024-07-26

Abstract excerpt

<title>Abstract</title> <p>The combination of isothermal amplification and CRISPR-Cas12a system is a valuable tool for detecting nucleic acids, especially in emergency situations or disease outbreaks. However, achieving compatibility between these technologies has been a challenge because the CRISPR reaction eagerly cleaves nucleic acid amplification template before isothermal amplification is complete. This stud...

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Identifiers and source

Literature Corpus work
cb5d3108-a2fa-564d-aaf2-305025f40a69
DOI
10.21203/rs.3.rs-4728949/v1
Open publication

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Enhancement of CRISPR-Cas12a System through Universal Circular RNA DesignDOI 10.21203/rs.3.rs-4728949/v1
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