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Novel nucleic acid detection strategies based on CRISPR-Cas systems: From construction to application.

Biotechnology and bioengineering - 1 Jul 2020

Zhu Chu-Shu, Liu Chuan-Yang, Qiu Xin-Yuan, Xie Si-Si, Li Wen-Ying, Zhu Lingyun, Zhu Lv-Yun

Abstract excerpt

Beyond their widespread application as genome-editing and regulatory tools, clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated (Cas) systems also play a critical role in nucleic acid detection due to their high sensitivity and specificity. Recently developed Cas family effectors have opened the door to the development of new strategies for detecting different types of nucleic...

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PMID: 32175589
DOI: 10.1002/bit.27334

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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