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Rationally-engineered reproductive barriers using CRISPR & CRISPRa: an evaluation of the synthetic species concept in <i>Drosophila melanogaster</i>

2018-02-02

Abstract excerpt

The ability to erect rationally-engineered reproductive barriers in animal or plant species promises to enable a number of biotechnological applications such as the creation of genetic firewalls, the containment of gene drives or novel population replacement and suppression strategies for genetic control. However, to date no experimental data exist that explores this concept in a multicellular organism. Here we ex...

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Literature Corpus work
c78915ec-7401-523d-8849-ba0fa8eaaa6a
DOI
10.1101/259010
Open publication

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