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Population suppression by release of insects carrying a dominant sterile homing gene drive targeting <i>doublesex</i> in <i>Drosophila</i>

2023-07-17

Abstract excerpt

Gene drive alleles, which bias their own inheritance and increase in frequency, show great promise for blocking disease transmission or directly suppressing pest populations. The most common engineered drive system is the CRISPR homing drive, which converts wild-type alleles to drive alleles in the germline of drive heterozygotes by homology-directed repair after CRISPR cleavage. One successful homing drive exampl...

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Identifiers and source

Literature Corpus work
7830c615-d8b1-50e4-89f8-530a589e4782
DOI
10.1101/2023.07.17.549342
Open publication

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Population suppression by release of insects carrying a dominant sterile homing gene drive targeting <i>doublesex</i> in <i>Drosophila</i>DOI 10.1101/2023.07.17.549342
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