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Article

A large-scale resource for tissue-specific CRISPR mutagenesis in <i>Drosophila</i>

2019-05-13

Abstract excerpt

<h4>SUMMARY</h4> Genetic screens are powerful tools for the functional annotation of genomes. In the context of multicellular organisms, interrogation of gene function is greatly facilitated by methods that allow spatial and temporal control of gene abrogation. Here, we describe a large-scale transgenic short guide (sg) RNA library for efficient CRISPR-based disruption of specific target genes in a constitutive o...

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Identifiers and source

Literature Corpus work
5765013f-89ac-5766-bcd9-cd95117a3f38
DOI
10.1101/636076
Open publication

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