Article

Diverse Functions Associate With Non-Coding Polymorphisms Shared Between Humans and Chimpanzees

2022-03-17

Abstract excerpt

<h4>Background: </h4> Long-term balancing selection (LTBS) can maintain allelic variation at a locus over millions of years and through speciation events. Variants shared between species in the state of identity-by-descent, hereafter “trans-species polymorphisms”, can result from LTBS, often due to host-pathogen interactions. For instance, the major histocompatibility complex (MHC) locus contains TSPs present acro...

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Literature Corpus work: c60f49cb-8ad5-58d3-8964-0955888dfd58
DOI: 10.21203/rs.3.rs-1445890/v1

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