Article

Signatures of long-term balancing selection in human genomes

2017-03-22

Abstract excerpt

Balancing selection maintains advantageous diversity in populations through various mechanisms. While extensively explored from a theoretical perspective, an empirical understanding of its prevalence and targets lags behind our knowledge of positive selection. Here we describe the Non-Central Deviation ( NCD ), a simple yet powerful statistic to detect long-term balancing selection (LTBS) that quantifies how clo...

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Identifiers and source

Literature Corpus work: 4377e6de-d021-5301-b602-6c74138b01d1
DOI: 10.1101/119529

Open publication

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