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Article

Diverse functions associate with non-coding polymorphisms shared between humans and chimpanzees.

BMC ecology and evolution - 23 May 2022

Velazquez-Arcelay Keila, Benton Mary Lauren, Capra John A

Abstract excerpt

BACKGROUND: Long-term balancing selection (LTBS) can maintain allelic variation at a locus over millions of years and through speciation events. Variants shared between species in the state of identity-by-descent, hereafter "trans-species polymorphisms", can result from LTBS, often due to host-pathogen interactions. For instance, the major histocompatibility complex (MHC) locus contains TSPs present across...

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PMID: 35606693
DOI: 10.1186/s12862-022-02020-x
PMCID: PMC9125839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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