Article
The rhesus macaque is three times as diverse but more closely equivalent in damaging coding variation as compared to the human.
BMC genetics - 29 Jun 2012
Yuan Qiaoping, Zhou Zhifeng, Lindell Stephen G, Higley J Dee, Ferguson Betsy, Thompson Robert C, Lopez Juan F, Suomi Stephen J, Baghal Basel, Baker Maggie, Mash Deborah C, Barr Christina S, Goldman David
Abstract excerpt
BACKGROUND: As a model organism in biomedicine, the rhesus macaque (Macaca mulatta) is the most widely used nonhuman primate. Although a draft genome sequence was completed in 2007, there has been no systematic genome-wide comparison of genetic variation of this species to humans. Comparative analysis of functional and nonfunctional diversity in this highly abundant and adaptable non-human primate could inform...
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