Article

Evaluating chromatin accessibility differences across multiple primate species using a joint modelling approach

2019-04-24

Abstract excerpt

Changes in transcriptional regulation are thought to be a major contributor to the evolution of phenotypic traits, but the contribution of changes in chromatin accessibility to the evolution of gene expression remains almost entirely unknown. To address this important gap in knowledge, we developed a new method to identify DNase I Hypersensitive (DHS) sites with differential chromatin accessibility between species...

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Literature Corpus work: 869b076e-0436-5d26-9905-d52620ad2b77
DOI: 10.1101/617951

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